Cyclohexane: Axial vs. Equatorial
In substituted cyclohexanes, the substituents can occupy
either axial or equatorial position. In general, the larger group
tends to prefer the equatorial position in order to avoid 1,3-diaxial
interactions, thus leading to a lower energy. In this tutorial, we
will examine the mono- and di-substituted cyclohexanes - their conformations
as well as their stereochemistry.
Which methylcyclohexane conformation is of higher energy
As ring-flip occurs, which conformation of cis-1,2-dimethylcyclohexane
is more stable?
Which conformation of trans-1,2-dimethylcyclohexane is
What is the relationship between cis and trans-1,2-dimethylcyclohexane?