1.In the Blood: In this report, doctors attempt to use a leukemia patient's own bone marrow as a source of life-saving stem cells. 2.Sickle Cell Anemia: The most common genetic disease in America is also one of the most painful and debilitating. But an experiment on mice has raised hopes with an anti-sickling gene therapy. 3.Using a Killer to Cure: This segment highlights work at MIT and Harvard to combat sickle-cell anemia - with a therapy derived from HIV. Transitioning from mice to human clinical trials is discussed. 4.Decoding Malaria: Increasingly drug-resistant and adaptable, malaria is a formidable foe. This report shows how scientists have cracked malaria's code and can begin to read its battle plans. 5.Tissues with Issues: What if transplant candidates didn't have to wait for organs? This segment spotlights pioneering attempts at tissue engineering. 6.Diabetes Cause and Cure: Scientists at the University of Washington have found the genetic source of Type 1 diabetes - the most severe form of the disease. And they owe their discovery to a very special rat. 7.Broken Hearts: Thousands of people die every year while waiting for a suitable heart transplant. In lieu of a human donor, scientists are working on three other solutions: the mechanical heart, the pig heart xenograft, and tissue engineering. 8.Longer Life for Livers: Damaged hearts and livers can remain functional with the help of machines, but the liver has no such support system - until now. This report looks at a device called MARS or Molecular Absorbent Recirculation System, the success of which will depend on genetic engineering. 9.The Test: Women are now regularly tested for breast cancer genes - sometimes leading to unusual choices. This segment profiles a woman who underwent a radical mastectomy, although she had shown no signs of cancer.