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Institutional Animal Care and Use Committee (IACUC)

December 14, 2021 @ 3:00 pm - 4:00 pm

Institutional Animal Care and Use Committee (IACUC)


03:00 pm

Video Conference Call


Meeting called to order at ____________ (Chair Long).

Attendance/Confirmation of Quorum

Approval of Minutes from September 30, 2021 IACUC Meeting.

Training Updates (Hagedorn)

Animal Care Training since last meeting:

Respirator Fit-Testing since last meeting:

Animal Facility/Maintenance Updates (Hagedorn)

Charles River serology results (10/30/21): All results for Streptobacillus moniliformis PCR testing of the thirteen-lined ground squirrels came back negative.

Occupational/Environmental Health and Safety: (Schill)

Institutional Biosafety Committee (IBC): IBC lab assessments will be coming soon (January-February)

Old Business (0)

New Business

Animal Use Protocols

Annual Continuing Reviews Since Last Meeting: (7) (Note: IACUC designates these reviews to IACUC Administrator Schill. Continuing review documents are available to all IACUC members in the protocol e-file upon request.)

(Year 1 and 2) Completed Since Last Meeting (5):

Protocol # 294-R1: Banding nestling peregrine falcons nesting at University of Wisconsin, Oshkosh (McPhee, Septon): Year 2 of project, 2 falcons banded, no problems reported.

Protocol# 298-R1: Pre-Hibernation Ground Squirrels as a Model of Obesity (Kurtz): Year 2 of project, 116 13-lined ground squirrels used, no problems reported.

Protocol # 249-R3: Feeding of Laboratory-Reared Mosquitoes on Anesthetized Gerbils (Michalski): Year 2 of project, no animals used on this protocol.

Protocol #244-R3: Parasitology Bio 354/554 Course Laboratory Exercises (Michalski): Year 2 of project, no animals used on this protocol.

Protocol #246-R3: Molecular Basis of Infectivity-microfilariae and maintenance of contingency life cycles for Filariasis Research Reagent Resource Center (FR3) (Michalski): Year 2 of project, 188 gerbils used, project is running smoothly.

Year 3/Project Summary (2):

Protocol #260-R2: Mammalian Hibernators: Research and Training (Merriman/Kurtz): Protocol went smoothly, and the PI’s renewal was submitted and approved via DMR.

Protocol #314: Treatment of rodents with bromodomain inhibitors (Michalski): Study was never conducted. Protocol was closed at request of PI.

New Animal Use Protocols (0)

Renewal of Animal Use Protocols (1)

Via Designated Member Review (1):

Protocol # 260-R3: Mammalian Hibernators: Research and Training (Merriman/Kurtz): Renewal was approved via DMR on 11/30/2021.

Via Full Committee Review (0):

Modification Requests to Animal Use Protocols (0)

Standard Operating Procedures (SOPs) (4) (Hagedorn)

New Standard Operating Procedures (0)

3 Year Renewal of Standard Operating Procedures (3)

SOP # 15: Monitoring Cage Wash Efficacy

SOP #28: Operation and Maintenance of Schlyer CBW1026 Cage Washer

SOP #44: Guidelines for Rodent Blood Collection

Updated/Modified Standard Operating Procedures (1)

SOP # 41: Daily Checks of Animal Facility: Updated with new backup system/Slack communication)

Unexpected Event/Problem Reports (0)

d. Post-Approval Monitoring (PAM): (1) (Gasper/Hagedorn)

i. Surgery observation

e. Updated Animal Care and Use Program Documents: (2)

i. Animal Care Manual

ii. Disaster/Emergency Response Plan and COVID-19 Response Supplement

f. Semi-Annual Program Review and Facility Inspections (document is in meeting folder): (Schill/Hagedorn)

i. Subcommittee conducted semi-annual facility inspection on 12/3/21.

ii. Program review to be completed with full committee at 12/14/21 meeting.

Items from IACUC Administration/Compliance (Schill):

USDA Inspection: VMO conducted a routine inspection on 10/18/21. No non-compliant items identified.

OLAW Animal Welfare Assurance renewal submitted on 10/31/21.

USDA Annual Report submitted on 11/1/21.

OLAW Annual Report submitted on 11/11/21.

USDA Issued final rule changes affecting IACUCs on November 24, 2021, in response to the 21st Century Cures Act. The rule removes the following requirements (effective on December 27, 2021):

Registered research facilities update their registration information every 3 years.

The IACUC at each facility conducts a continuing review of research activities involving animals. Instead, it requires a complete resubmission and review of such activities at least every 3 years. This change harmonizes the timeline for the complete review process with that of the NIH OLAW.

Research facilities request an inactive status if they no longer use, handle, or transport AWA-covered animals.

The USDA also clarifies the duration of a registration and conditions for its cancellation. Furthermore, it will no longer require that the Institutional Official or Chief Executive Officer sign the annual report. This final rule can be viewed in the Federal Register.

USDA Update on Contingency Planning: On December 3, 2021, the USDA APHIS issued a final rule which will become effective on January 3, 2022.

The rule establishes regulations under which research facilities and dealers, exhibitors, intermediate handlers, and carriers must meet certain requirements for contingency planning and personnel training. The rule will better ensure that entities responsible for animals regulated under the Animal Welfare Act are prepared to safeguard the health and welfare of animals if emergencies or disasters strike. This final rule can be viewed in the Federal Register.

OLAW Guidance on Grant to Protocol and Contract to Protocol Congruence:

In response to the 21st Century Cures Act to reduce administrative burden, two new Guide Notices are available. OLAW provides clarification on grant to protocol congruence review in NOT-OD-22-005 and contract to protocol congruence review in NOT-OD-22-006. These Guide Notices clarify:

the requirement for congruence review,

the responsibility for congruence review,

timing and verification of congruence review by IACUC approval, and

methods for conducting congruence review.

Items from Chair (Long):

Items from the Veterinarian (Gasper):

Items from the IACUC:

Items from the floor (guests):

Meeting Adjourned at ___________ (Long).

Upcoming Meetings:

Thursday, January 27, 2022 @ 3:00 PM via Microsoft Teams

Doodle poll will be sent to schedule spring meetings

Protocol submission deadlines posted on website under IACUC Meetings tab.

Kelly Schill



December 14, 2021
3:00 pm - 4:00 pm