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Shelly Michalski, M.S., Ph.D.

by Michalski, Michelle L last modified Apr 01, 2013 11:15 AM

Start here to find out more about Dr. M's classes and research.

EDUCATION

  • Ph.D. Molecular Microbiology and Microbial Pathogenesis, Washington University School of Medicine 2000
  • M.S. Veterinary Microbiology (Parasitology) University of Missouri–Columbia 1993
  • B.A. Biology (Pre-veterinary) Augustana College 1990

COURSES TAUGHT AT UWO

Registered students can access all course materials through D2L

RESEARCH INTERESTS

Our lab is primarily interested in lymphatic filariasis, a tropical disease caused by mosquito-borne nematodes.  We study the interaction of the microfilaria stage of filarial nematodes with their arthropod vector, filarial transcriptomics, and also naturally occurring filarial parasites of Wisconsin wildlife.  
 

1.  Molecular determinants of microfilarial infectivity

2.  Filarial transcriptomics

3.  Filarial parasites of wildlife 

PUBLICATIONS

 Choi YJ, Ghedin E, Berriman M, McQuillan J, Holroyd N, Mayhew GF, Christensen BM, and ML. Michalski.  2011. A Deep Sequencing Approach to Comparatively Analyze the Transcriptome of Lifecycle Stages of the Filarial Worm, Brugia malayi.  PLoS NTD 5(12): e1409.

 Michalski ML, Griffiths KG, Williams SA, Kaplan RM, Moorhead AR. 2011.  The NIH-NIAID Filariasis Research Reagent Resource Center. PLoS Negl Trop Dis 5(11):e1261.

 Michalski ML, Erickson SM, Bartholomay LC, Christensen BM.  2010. Midgut barrier imparts selective resistance to filarial worm infection in Culex pipiens pipiens. PLoS Negl Trop Dis. 2010 Nov 2;4(11):e875.

 Griffiths K.G., Alworth L.C., Harvey S.B., and Michalski M.L.  2010. Using an intravenous catheter to carry out abdominal lavage in the gerbil.  Lab Animal 39(5):143-8.

 Michalski M.L., Bain O., Fischer K., Fischer P., Kumar S., and Foster J.  2010.  Identification and phylogenetic analysis of Dirofilaria ursi (Nematoda:Filarioidea) from Wisconsin black bears (Ursus americanus) and its Wolbachia endosymbiont.  J. Parastiol. 96(2): 412-9.

Griffiths K.G., Mayhew G.G., Zink R.L., Erickson S.M., Fuchs J.F., Mcdermott C.M., Christensen B.M., and M.L. Michalski.  2009.  Use of microarray hybridization to identify Brugia genes involved in mosquito infectivity.  Parasitology Research  106(1):221-35.

 J. P. Dubey , M. C.  Jenkins , O. C. H. Kwok , R. L. Zink, M. L. Michalski, V. Ulrich, J. Gill , M. Carstensen , P. Thulliez. 2009  Seroprevalence of Neospora caninum and Toxoplasma gondii antibodies in white-tailed deer (Odocoileus virginianus) from Iowa and Minnesota using four serologic tests.  Veterinary Parasitology 161(3-4): 330-4.

Todd Anderson, Amanda DeJardin, Daniel K. Howe, J. P. Dubey, Michelle L Michalski.  2007. Neospora caninum antibodies detected in Midwestern white-tailed deer (Odocoileus virginianus) by Western Blot and ELISA. Veterinary Parasitology 145:152-55. 

ML Michalski, Bates KM, Essar DW, Rosenfield C, Erickson M, Selle R, Massung RF. 2006.  Prevalence of Anaplasma phagocytophilum in Central and Western Wisconsin . Parasitol. Res. 99(6):694-699. 

Dana K. Vaughan, Aaron R. Gruber, Michelle L. Michalski, Jeffrey Seidling, and Sarah Schlink.. 2006  Capture, Care, and Captive Breeding of 13-lined Ground Squirrels, Spermophilus tridecemlineatus. Lab Animal 35(4):33-40. 

ML Michalski, JD Monsey, DP Cistola and GJ Weil.  2002.  An embryo-associated fatty acid-binding protein in the filarial nematode Brugia malayi.  Molecular and Biochemical Parasitology 124:  1-10. 

Michalski ML and Weil GJ.  1999.  Gender-specific gene expression in Brugia malayi. Mol. Biochem. Parasit.  104:247-257. 

Ismail MM, Jayakody RL, Weil GJ, Nirmalan N, Jayasinghe KSA, Abeyewichrema W, de Silva C, Rezvi Shoriff MH, Rajaratnam H, Amarasakera N, Michalski M, and Dissanaike AS.  1998.  Efficacy of single dose combinations of albendazole, ivermectin and diethylcarbamazine in the treatment of bancroftian filariasis.  Trans. Royal Soc. Trop. Med. Hyg.  92: 94-97.

Marley SE, Michalski ML, Corwin RM and Van Schoyck M.  1993.  Fecal Shedding of Toxocara canis and Ancylostoma caninum eggs by dogs receiving commerical anthelmintics.  Canine Practice (18)2:  7-12.

SUPPORT

NIH/NIAID Filariasis Research Reagent Resource Center  (Subcontract with University of Georgia) September 2011-Sept 2012 (Acanthacheilonema viteae production)

UWO Faculty Development Program, 2011:  Filarial Nematode Morphology

University of Georgia, 2009-2012:  NIH-FUNDED FILARIASIS RESEARCH REAGENT RESOURCE CENTER (Director of Communication, Project Liaison)

UWO Faculty Development Program Research Component, 2009-2010:  PATHOGEN COMPETITION IN MOSQUITOES

UWO Faculty Development Program Sabbatical Program, 2009:  IDENTIFYING FILARIAL WORM COMPONENTS THAT CORRELATE WITH MOSQUITO INFECTIVITY

University of Kentucky, 2009-2010:  Bill and Melinda Gates Foundation, SUPPLEMENTAL VECTOR INTERVENTION REQUIRED TO ELIMINATE LYMPHATIC FILARIASIS IN THE SOUTH PACIFIC

NIH Academic Research Enhancement Award, 2006-2009:   MOLECULAR BASIS FOR INFECTIVITY OF BRUGIA MALAYI MICROFILARIAE 

NIH Administrative Supplement Providing Summer Research Experiences for Students and Science Educators, 2009:  MOLECULAR BASIS FOR INFECTIVITY OF BRUGIA MALAYI MICROFILARIAE

 

 

 

 

 

AT PLAY

With school, science, and family - have fun!
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Shelly tubing
 

 

 

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by Michalski, Michelle L last modified Apr 01, 2013 11:15 AM